BME VBK · Department of Organic Chemistry and Technology

Innovative Pharmaceutical and Chirotechnological Research Group

Preparation of biologically active compounds by modern synthetic methods — from multicomponent reactions to flow chemistry, using reactors of our own design.

Multicomponent reactions Total syntheses Microwave technique Flow chemistry 3D printing Cyclodextrin chemistry Organometallic chemistry Stereochemistry Resolutions
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Spirooxindole–dihydropyridine bisphosphonate Prepared by microwave-assisted multicomponent synthesis — a compound from our own research
Collaboration

Our industrial partners

Anthelos Kft.
Bálint Analitika Kft.
CycloLab Ltd.
Egis Pharmaceuticals Plc.
EUROAPI
Richter Gedeon Plc.
Servier Research Institute Ltd.
ThalesNano Inc.
Our projects

Research areas

Mutually reinforcing areas, from fundamental research to scaled-up synthesis.

Details
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Multicomponent reactions

Atom-efficient syntheses: complex molecular architectures built in a single step.

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Total syntheses

Complete synthesis of biologically active inhibitor candidates by retrosynthetic planning.

Microwave technique

Shorter reaction times, improved selectivity and better energy efficiency.

Flow chemistry

Continuous flow reactor systems for scaling up our syntheses.

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3D-printed reactors

Custom-designed microreactors from chemically resistant polymers and composites.

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Organometallic chemistry

Organolithium reactions at low temperature with chiral and achiral substrates.

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Cyclodextrin chemistry

CD derivatives with unique properties, inclusion complexes and formulation studies.

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Stereochemistry and resolutions

Preparation of enantiopure compounds and chiral separation techniques.

In numbers

Our research and results

International publications, industrial partnerships, national and international grants.

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93
Peer-reviewed publications
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56
Patents filed
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4+
Active research projects
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25+
Research group members
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1800+
Total citations
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179 400
Horizon Europe funding (EUR)
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Recent news

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Members of the Innovative Pharmaceutical and Chirotechnological Research Group
The research group · BME Faculty of Chemical Technology and Biotechnology, Budapest